Fabulous! Thanks to the fantastic care and expertise of Dr. Pabon and his staff, I was able to conceive and deliver a healthy beautiful baby! I had the most amazing experience working with Dr. Pabon and his staff. I always felt that I received compassion, personal care, and detailed attention throughout both of my IVF procedures. Dr. Pabon and his staff were caring, compassionate, and seemed to be available with any needs or questions while consistently remaining on top of all of my medical needs. I always felt listened to, supported, and was given all the time that I needed with any questions/answers. I would absolutely recommend Dr. Pabon and his staff for anyone needing fertility assistance. Thank you Dr. Pabon and staff… I will forever be grateful to you all!
I cannot say enough good things about Dr Pabon and his staff! I sought him out after 3 miscarriages due to a genetic chromosome translocation. I had consulted with other doctors and very much felt like another number, but after a consultation with Dr Pabon I was very impressed and felt that he was up to date with all the latest research, and also a very kind and compassionate man. I traveled from Tampa to Sarasota for treatment. He was able to detect another issue which could have prevented me getting pregnant and at my request (purely due to financial issues), assisted me in finding someone within my insurance network to correct it, and continued to coordinate my care during that time. When that was done, I was back with Dr Pabon and have had nothing but a positive experience. I have never seen a doctor go above and beyond like he does – and I work in the medical field. I have paged him with issues on the weekend and he is prompt to reply, even going as far as calling medication in to my pharmacy when needed. I am now pregnant due to an IVF/PGS/FET cycle and will forever be grateful to him and his staff for their excellent care.
From “K. BOO as seen in Google reviews, April 2013
Twin and higher order pregnancies are considered a complication of IVF and super-ovulation. Twin and Higher order pregnancies can end prematurely in more than 70% of cases. Pre-term birth is very dangerous for babies. There can be respiratory, vascular, intestinal, infectious, and brain complications that can lead to a life of disability.
IVF patients have been asking on a weekly basis for twin pregnancies. Patients say things such as “twins are cute,” or “I only want to go through one pregnancy,” or “I am older and only want to go through one more pregnancy.” Some patients also focus on the cost of ART treatments and the desire to increase the chance of a live birth by implanting more embryos. I assure you that the cost of the NICU and the care that a pre-term baby or babies with short term or long term morbidities may require is many, many, many times higher that the cost of many IVF tries.
Up until recently, we have usually transferred one or two embryos into younger patients early in the process. Sometimes more embryos are transferred in special situations.
Recently, technologies have changed. One such change has been the new freezing technology called Vitrification. With this technology, the pregnancy chance with a fresh embryo transfer is similar to that of a frozen/thawed embryo transfer. Therefore, there is not a “fear” of freezing embryos anymore. In the past, frozen/thawed embryo transfer pregnancy rates were a fraction of a fresh transfer. Nowadays, the transfer of a frozen/thawed embryo into a “programmed” uterus many times has a higher chance of pregnancy than the transfer of a fresh embryo into a hyper stimulated patient. That is why many patients hear the “all freeze” protocol information in our consultations. The better freezing technologies present patients with the choice of transferring one embryo at the time.
Unfortunately, a single embryo transfer carries a lower chance of pregnancy than when 2 or 3 are transferred. Most younger patients can expect a chance of pregnancy with a single embryo in the range of 35-40%. So, commonly, patients will ask for two.
Recently there is a whole new technology that is really a game changer. Pre implantation genetic screening of embryos at the blastocyst stage yields such good data that patients can expect a chance of pregnancy in excess of 80% per transfer per single embryo. The reason for this huge jump is that the single embryo being transferred has been shown to carry the normal number of chromosomes by very powerful technology.
With pregnancy rates in excess of 80% per “normal” embryo transferred (normal within the limits of the technology), then transferring two such tested embryos is essentially a planned twin pregnancy.
I have been trying to counsel our patients to accept single embryos for transfer, but many are still pushing and pushing. At this time we can manage cases on a one on one basis, but patients should educate themselves of the risks to themselves and their babies. I have discussed this issue with our Maternal Fetal Medicine consultants and they all support the transfer of single embryos after PGS with trophectoderm blastocyst biopsies and 24 chromosome microarray complete genomic hybridization.
I will follow this post with the American Society of Reproductive Medicine document about multiple pregnancies.
Julio E. Pabon, M.D., F.A.C.O.G.
CEO Fertility Center and Applied Genetics of Florida
Assistant Clinical Professor/Florida State Univ. College of Medicine
You have been selected this year as one of America’s “Top Doctors” practicing in the field of Reproductive Endocrinology by Castle-Connolly and their physician-led team of researchers. Your selection is based upon anonymous nominations by area medical professionals.
For the 12th year, Castle-Connolly Medical Ltd. (America’s trusted source for identifying Top Doctors and The Best in American Medicine) has selected Sarasota Magazine as its exclusive partner to publish its Top Doctors list because of the excellence of our editorial content and the integrity of our audited circulation.
Three sisters attended IVF clinic in Sarasota, Florida over several years. They all required IVF and Pre-implantation Genetic diagnosis due to different reasons. Two have had children while the youngest is now pregnant with her first child.
Infertility affects 15% of couples. Those that require the most advanced treatments such as In vitro fertilization and embryo transfer procedures now have to decide if they should also have pre-implantation genetic screening (PGS or PGD) of their embryos. The more common indications for PGD are advanced maternal age, previous known genetic disease, previous multiple miscarriages, and previous IVF failures. The present sisters are remarkable because It is extremely rare to have so many siblings require PGD when there is no known genetic disease.
The first sister was treated in 2007. This resulted in the birth of a boy after she had failed multiple IVF treatments in other clinics. She was in her mid thirties. The second sister attended was treated in 2008 at the age of 39. This resulted in the birth of a girl. the third sister was treated in 2012. Her initial IVF/PGD treatment cycle resulted in all abnormal embryos. There was no embryo transfer. At the second treatment there were normal embryos available for transfer. She is currently pregnant. These cases emphasize the fact that all humans make chromosomaly abnormal embryos. The risk of this increases remarkably after the age of 33. This is because in humans the eggs are in a state of arrested cell division for the entire life of the person. The longer one waits to start a family, the more errors that can occur in the final maturation of the eggs. This is why pregnancy chances decrease with age, miscarriages increase with age, and the risk of conditions like Down’s syndrome also increase with age. Patients and prospective parents need to understand that waiting can be risky. Patients also must be aware that if their fertility journey takes them to IVF, that they must be counseled regarding the option of pre-implantation genetic diagnosis.