In the March issue of Obstetrics & Gynecology there are two committe opinions that recommend expanded carrier screening for recessive genetic disorders. This is due to the lower costs of expanded testing in our current age of “Genomic Medicine.” Pre-conception genetic screening gives future parents valuable information as there are currently commonly employed technologies that can prevent the birth of an affected child. Couples have the very viable option of Pre-implantation Genetic Disease (PGD) screening of embryos through “in vitro” fertilization procedures. The committe opinions are well written and I plan to use them as part of my informed consent process.
J V Productions Plans a Fertility IVF TV Show 2015. This is the Casting Call.
A renowned television production company is seeking families for a new series surrounding fertility.
JV Productions Inc. are the producers behind the hit shows Selling New York and Selling L.A. They are a Canadian-based and family-operated company that’s mandate is to produce high quality and engaging television programming.
They are currently casting for a new series that will follow several fertility clinics across the U.S. and the families that come through their doors. JV wants to highlight the struggles and triumphs of families seeking fertility assistance in order to bring new life into this world; and to showcase the new medical and technological advancements that are changing the way we make and define family.
Are you interested in sharing your story with a North American television audience? If so, please contact firstname.lastname@example.org. She is delighted to hear your personal stories and answer any questions you may have.
The United States Supreme Court ruled today in a 5 to 4 vote that same sex marriages are legal and constitutional. This is a momentous step in extending liberty and rights to all Americans.
Many of our patients will benefit from the ruling by having rights that the relationship of marriage grants them. This has implications to medical decisions, wills, insurance, and many other areas. Our gay and lesbian parents will surely gain better parenting rights and in the short term our same sex male married parents will soon have the ability to have their names appear on the birth certificate of their baby immediately at birth.
In our society, marriage is both a legal state and in most cases, a religious union. It is impressive how our country is so free and well founded that our Supreme Court ruled in favor of same sex marriage despite expected resistance from some organized religious leaders.
Protecting the rights and liberties of the few, protects us all.
Julio E. Pabon, M.D.
Dr. Julio E. Pabon,
Greetings! You have been nominated again this year as one of Sarasota’s Top Doctors. For the 14th year, Castle-Connolly Medical Ltd. (America’s trusted source for identifying Top Doctors through peer nominations and The Best in American Medicine) has selected Sarasota Magazine as its exclusive partner to publish its annual Top Doctors list because of the excellence of our editorial content and the integrity of our audited circulation.
Keith C. Magnuson
I am a frequent watcher of Fox and Friends in the morning. I have enjoyed their show as well as the medical “A” team. The medical “A” team has always been quite objective and interesting.
I was surprised on Feb 20th, 2014, when I saw and heard Dr. Marc Siegel comment on new PGD technology that allows us to test embryos for the presence of the BRCA Breast Cancer Mutations. The usually objective Dr. Seigel seemed to be fine with the test, but then went on to share his anxiety about the potential of PGD to lead us down the pathway of genetic engineering and the possibility that we may create an “evil super race” akin to the evil super beings from “Star Trek.” I was surprised to see Dr. Seigel go down the road of the news correspondent that tries to sensationalize a story for ratings.
Dr Siegel should have emphasized that Pre-implantation Genetic Diagnosis allows physicians like me to treat a family and many subsequent generations. There are many horrible genetic mutations that lead to severe morbidity and the early death of children. A mother that has lost a baby in her arms due to one of these conditions like cystic fibrosis or spinal muscular atrophy or a family that has dealt with the severe mental afflictions of Fragile X should have the choice to grow their family with much reduced risk of the known disease that they wish to avoid. Dr. Seigel did acknowledge the usefulness of PGD in these severe and lethal conditions, but should not criticize families that may choose to modify the risk of a condition like breast cancer in their offspring. Statements like the ones made on Fox and Friends alluding to physicians like me may potentially create an “evil superhuman race” are incendiary at the least and should not be made by a true man of science.
Twenty seven years ago I chose my career path with the hope that I would be able to apply genetic knowledge for the prevention of human afflictions. Now it is part of my daily practice. It is a powerful practice that inspires and humbles at the same time when we choose to implant a human pre-embryo that we know is free of the affliction to which his or her older sibling succumbed.
Julio E. Pabon, M.D. , F.A.C.O.G.
Fertility Center and Applied Genetics of Florida
Our Tampa / Sarasota IVF Clinic leads in the application of new PGS / PGD IVF technology in Florida. Our results from our 2012 IVF with PGS / PGD Blastocyst Laser assisted trophectoderm biopsy program show that patients that had a single euploid (number of chromosomes) embryo implanted had great success. Patients that had fresh single embryo transfer achieved a pregnancy in 75% of cases. More than 90% of patients who were treated with “all freeze” protocols followed by single euploid transfers achieved a pregnancy. These results exclude patients that had abnormal endometrial lining development.
New IVF technology has allowed us to increase the probability of a normal pregnancy while limiting serious complication of Assisted Reproductive Technology associated with multiple pregnancies. Our program has also eliminated severe ovarian hyper-stimulation as a complication due to our lupron trigger protocol and “all freeze” protocols.
Contact us at (941) 787-2287 or at www.geneticsandfertility.com or www.drpabon.com
Julio E. Pabon, M.D. from Fertility Center and Applied Genetics of Florida and Gwendolyn Quinn, PhD from Moffitt Cancer Center will be discussing Oncofertility in a continuing medical education meeting on September 28, 2013. More information is available through smh.com
Here is the meeting agenda:
Dr. Julio Pabon,
You have been selected this year as one of America’s “Top Doctors” practicing in the field of Reproductive Endocrinology by Castle-Connolly and their physician-led team of researchers. Your selection is based upon anonymous nominations by area medical professionals.
For the 12th year, Castle-Connolly Medical Ltd. (America’s trusted source for identifying Top Doctors and The Best in American Medicine) has selected Sarasota Magazine as its exclusive partner to publish its Top Doctors list because of the excellence of our editorial content and the integrity of our audited circulation.
All my best,
Keith C. Magnuson
Three sisters attended IVF clinic in Sarasota, Florida over several years. They all required IVF and Pre-implantation Genetic diagnosis due to different reasons. Two have had children while the youngest is now pregnant with her first child.
Infertility affects 15% of couples. Those that require the most advanced treatments such as In vitro fertilization and embryo transfer procedures now have to decide if they should also have pre-implantation genetic screening (PGS or PGD) of their embryos. The more common indications for PGD are advanced maternal age, previous known genetic disease, previous multiple miscarriages, and previous IVF failures. The present sisters are remarkable because It is extremely rare to have so many siblings require PGD when there is no known genetic disease.
The first sister was treated in 2007. This resulted in the birth of a boy after she had failed multiple IVF treatments in other clinics. She was in her mid thirties. The second sister attended was treated in 2008 at the age of 39. This resulted in the birth of a girl. the third sister was treated in 2012. Her initial IVF/PGD treatment cycle resulted in all abnormal embryos. There was no embryo transfer. At the second treatment there were normal embryos available for transfer. She is currently pregnant. These cases emphasize the fact that all humans make chromosomaly abnormal embryos. The risk of this increases remarkably after the age of 33. This is because in humans the eggs are in a state of arrested cell division for the entire life of the person. The longer one waits to start a family, the more errors that can occur in the final maturation of the eggs. This is why pregnancy chances decrease with age, miscarriages increase with age, and the risk of conditions like Down’s syndrome also increase with age. Patients and prospective parents need to understand that waiting can be risky. Patients also must be aware that if their fertility journey takes them to IVF, that they must be counseled regarding the option of pre-implantation genetic diagnosis.
Dr. Pabon, C.E.O., Medical and Laboratory Director of Florida’s premier IVF center will attend the London Fertility Show in November 2013. He and his staff will be at booth 18 during the meeting to answer questions about all aspects of IVF and assisted reproductive techniques and how we help patients from Europe. Please view our web site at www.geneticsandfertility.com or www.drpabon.com for further information.